Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4
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چکیده
منابع مشابه
Oligosaccharides of Hyaluronan Activate Dendritic Cells via Toll-like Receptor 4
Low molecular weight fragmentation products of the polysaccharide of Hyaluronic acid (sHA) produced during inflammation have been shown to be potent activators of immunocompetent cells such as dendritic cells (DCs) and macrophages. Here we report that sHA induces maturation of DCs via the Toll-like receptor (TLR)-4, a receptor complex associated with innate immunity and host defense against bac...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2002
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20001858